Climate Change and Global Health: An Interconnected Review

Mary Christine Wheatley
Wheatley Research Consultancy, Bagley, Minnesota, USA
Correspondence to: mchristinewheatley@gmail.com

DOI: https://doi.org/10.70389/PJES.100008

Additional information

• Ethical approval: N/a
• Consent: N/a
• Funding: No industry funding
• Conflicts of interest: N/a
• Author contribution: Mary Christine Wheatley – Conceptualization, Writing – original draft, review and editing
• Guarantor: Mary Christine Wheatley
• Provenance and peer-review:
  Commissioned and externally peer-reviewed
• Data availability statement: N/a

Keywords: Vector-borne diseases, Food security, Public health infrastructure, Climate adaptation strategies, International health cooperation.

Peer Review
Received: 27 July 2024
Revised: 17 October 2024
Accepted: 17 October 2024
Published: 5 November 2024

Introduction

Climate change, a pervasive force reshaping our planet, impacts nearly every facet of human life, not least of which is health. As global temperatures rise, the consequences extend beyond the environmental to the biological, influencing disease patterns and challenging public and food security systems worldwide.¹ This review delves into the profound effects of climate variations on vector-borne diseases, food security, and the overall public health landscape, exploring both the impacts and the adaptive strategies countries have implemented in response. Vector-borne diseases, such as malaria, dengue, and Zika, are highly sensitive to climatic conditions that affect vector habitats, life cycles, and the pathogens themselves.² Similarly, food security—a critical issue for global health—is at risk as climate change affects crop production, livestock health, and fisheries, all vital components of the world’s food supply.³ Public health responses are equally crucial, as they represent systemic efforts to mitigate and adapt to the health challenges posed by a changing climate.4 Exploring these interconnected themes, this article aims to provide a comprehensive analysis supported by current research, highlighting the necessity for ­integrated global efforts to address the multi-faceted challenges of climate change on health.

Climate Change and Vector-Borne Diseases

Overview of Vector-Borne Diseases

Vector-borne diseases, which are infections transmitted by the bite of infected arthropod species, such as mosquitoes, ticks, and flies, represent a significant global health burden. Examples include malaria, dengue, Zika virus, and chikungunya, each posing unique challenges to public health systems.5 These diseases are highly sensitive to climatic conditions, which influence the distribution, density, and infectivity of vector populations.⁶ Malaria, caused by Plasmodium parasites transmitted through the bites of infected Anopheles mosquitoes, remains one of the most severe public health challenges, particularly in sub-Saharan Africa and South Asia.⁷ Dengue, with its rapid global spread, is predominantly transmitted by Aedes aegypti mosquitoes and is notably responsive to meteorological factors, particularly temperature and rainfall patterns.⁸ The Zika virus, also spread by Aedes mosquitoes, has drawn significant attention due to its rapid emergence and the severe neurological defects it can cause in newborns when pregnant women are infected.⁹ The interplay between climate change and these diseases is complex, as rising temperatures and changing precipitation patterns can expand the geographical range of vectors and increase the periods of the year during which they are active. Such changes are likely to alter the transmission dynamics of these diseases, potentially leading to increased incidence and expansion into new areas, posing further challenges to global health security.²

Impact of Climate Change on Vectors

Climate change significantly affects the ecology and distribution of disease vectors such as mosquitoes and ticks through rising temperatures and altered precipitation patterns.¹⁰ Higher temperatures can accelerate the life cycle of vectors, thereby increasing their population size and the frequency of disease transmission.¹¹ Additionally, warmer climates can expand the geographical range of vectors, allowing them to inhabit previously unsuitable areas, thus increasing the risk of vector-borne diseases in new regions.¹² Changes in rainfall patterns are equally critical, as increased rainfall can provide more breeding sites for mosquitoes, whereas drought can concentrate populations around limited water sources, both scenarios potentially boosting the transmission of diseases like malaria and dengue.¹³ Extreme weather events, such as hurricanes and floods, can disrupt existing vector control measures, spreading vectors to new areas and creating emergency health situations where disease surveillance and control are more challenging.¹⁴ The combined impact of these climatic factors necessitates a dynamic approach to public health strategies, as the traditional spatial and temporal patterns of vector-borne diseases are transforming, requiring adjustments in monitoring, prevention, and control efforts. This adaptability is crucial to manage the anticipated increase in the spread of these diseases due to climate change.¹⁵

Case Studies and Data

Several regions around the world offer insightful examples of how climate change influences vector-borne diseases. In East Africa, the variability in climate ­patterns, particularly increased temperatures and inconsistent rainfall, has significantly extended the breeding seasons of Anopheles mosquitoes. This change facilitates not only a higher frequency of malaria outbreaks but also an expansion of the geographical areas affected. Research from the region has documented a clear correlation between these climatic anomalies and the rise in malaria cases, highlighting the potent influence of climate change on disease dynamics.¹⁶ Additionally, the fluctuating climatic conditions disrupt traditional seasonal patterns, confusing preventive efforts and healthcare planning. Studies in Kenya and Tanzania have shown that during years of higher than average temperatures coupled with sufficient rainfall, mosquito populations peak unusually early, leading to earlier-than-expected malaria outbreaks.¹⁷ Another study focused on the Ethiopian Highlands noted that even slight increases in temperature have allowed malaria to emerge in areas previously considered too cold for mosquito survival.¹⁸ These findings are supported by satellite data and on-ground temperature measurements, which provide a clear link between climate change and increased malaria transmission risk in East Africa.¹⁹ Moreover, climate projection models suggest that these conditions will worsen, potentially expanding the risk of malaria to higher altitudes and previously unaffected regions.²⁰

In South America, the case of Brazil exemplifies the impact of climate change on vector-borne diseases, specifically dengue fever. Rising temperatures have facilitated the proliferation of the Aedes aegypti ­mosquito, the primary vector for dengue, leading to an expansion of the disease’s geographical range. A 2021 study focusing on southern Brazil revealed that as average temperatures have risen, dengue incidence has climbed, marking a significant shift in the disease’s geographic range farther south than previously observed.²¹ The study highlights that the areas previously considered too cool for Aedes aegypti are now experiencing frequent outbreaks due to warmer climates.² Further supporting this, predictive models indicate that if the current warming trends continue, regions such as the Brazilian highlands could soon become hotspots for dengue transmission. This ­projection is based on the enhanced suitability of these areas for mosquito survival and reproduction as temperatures rise.²² Another recent study from Colombia and Venezuela reports similar trends, where higher ­temperatures and altered precipitation patterns have significantly increased the risk of dengue outbreaks by extending the mosquitoes’ active seasons and expanding their suitable habitats.²³ These findings are critical for public health planning and response strategies, as they suggest that future control measures must consider the evolving climatic conditions that could further facilitate the spread of dengue and other vector-borne diseases across South America.²⁴

In Southeast Asia, the role of El Niño in exacerbating dengue outbreaks has become increasingly evident. The phenomenon, which brings about significant fluctuations in rainfall, disrupts typical weather patterns, creating environments conducive to the breeding of Aedes mosquitoes. A comparative analysis across ­several countries in the region, including Thailand, Indonesia, and the Philippines, found that El Niño events correlate strongly with spikes in dengue cases due to enhanced mosquito breeding conditions.²⁵ This study highlighted the critical need for targeted public health responses during El Niño years to mitigate the impact on dengue transmission.²⁶

Moreover, recent research has extended these findings to suggest that not only do El Niño cycles influence dengue dynamics but so do La Niña conditions, which typically result in opposite climatic changes. During La Niña, increased rainfall can also lead to more stagnant water sites, ideal for mosquito larval development. This dual impact underscores the complex relationship between climatic anomalies and vector-borne disease prevalence in the region^.27 A 2022 study from Vietnam supports this, illustrating a clear link between the increased frequency of extreme weather events and higher dengue incidence, necessitating more robust vector control and disease surveillance systems.²⁸ These insights are crucial for regional health ­authorities, indicating the need for adaptable disease prevention strategies that account for the variability in climate patterns. As such, forecasting models that integrate meteorological data are being developed to better predict and respond to future outbreaks, ensuring that health systems can remain resilient even as climate change continues to alter disease landscapes in Southeast Asia and beyond.²⁹

Climate Change and Food Security

Overview of Food Security Challenges

Food security encompasses the assurance that all people have access to sufficient, safe, and nutritious food that meets their dietary needs for an active and healthy life at all times. It is built on four main pillars: availability, access, utilization, and stability.³⁰ Availability refers to the consistent and sufficient quantity of food available on a global, national, or local scale. Access involves having adequate resources to obtain appropriate foods for a nutritious diet, while utilization ­relates to how the body uses the nutrients in the food, influenced by factors like illness and proper cooking.³¹ ­Stability addresses the need for food availability, ­access, and utilization to be stable over time, not fluctuating dramatically even in the face of challenges such as economic crises or climatic shocks. The impact of climate change on food security is profound and multifaceted, affecting each of these pillars in significant ways.

Rising temperatures, unpredictable weather patterns, and increased incidence of extreme weather events like droughts and floods directly threaten food production, influencing crop yields, disrupting harvesting schedules, and reducing livestock productivity.³ Moreover, climate change can exacerbate food access inequalities by disrupting supply chains and increasing food prices, making healthy diets less affordable and accessible, particularly for marginalized populations in both urban and rural settings.³² As the global climate continues to change, the ­challenge of maintaining food security intensifies, necessitating comprehensive strategies that address the resilience of agricultural systems and food distribution networks. Enhanced agricultural practices, improved water management, and innovative technologies are critical to adapt to changing climatic conditions and ensure a stable food supply for the future.³³

Food Security and Economic Stability

Impact on Agriculture: Shifts in agricultural productivity, primarily resulting from altered climatic conditions, have a profound impact on the GDP of agrarian economies.³⁴ For instance, an increase in temperature and variability in rainfall have been shown to significantly reduce crop yields, which directly affects the economic stability of countries heavily reliant on agriculture.³⁵ The Intergovernmental Panel on Climate Change (IPCC) reports that these climatic changes have led to reduced yields of staple crops such as wheat and maize, which are critical to the economies of many developing countries.³⁶ Furthermore, livestock productivity is also compromised due to heat stress and changes in fodder availability, impacting both food security and agricultural income.³⁷ The economic implications are severe, with reductions in agricultural output potentially decreasing national GDPs by several percentage points, exacerbating poverty and economic instability in these regions.³⁸

Supply Chain Disruptions: Climate change-induced disruptions in food supply chains exacerbate economic instability by causing significant increases in food prices, especially impacting poor and vulnerable populations.³ These disruptions often result from extreme weather events such as droughts and floods, which not only reduce agricultural output but also hinder transportation and distribution of food, leading to supply shortages and price spikes.^38,39 For instance, in Southeast Asia, typhoons have caused substantial disruptions in the rice supply chain by directly damaging agricultural infrastructure. Significant typhoon events, like Typhoon Haiyan, have not only devastated rice fields but also hindered transportation and ­distribution systems, resulting in severe delays in rice supply. This damage has led to a reduction of up to 12.5 million tons of rice since 2001, contributing to notable increases in regional market prices as availability decreases.⁴⁰ Such volatility particularly affects urban poor who spend a larger portion of their income on food and have limited access to alternative food sources.⁴¹ The resultant economic instability can trigger broader social issues, ­including food riots and ­increased poverty rates, ­further compounding the challenges faced by these communities.⁴²

Direct and Indirect Effects of Climate Change on Agriculture

Crop Yields: Climate change significantly impacts agricultural productivity, with temperature increases and altered rainfall patterns posing major threats to crop yields. Rising temperatures can accelerate crop maturation, reducing growing periods and consequently decreasing yield.³⁵ Furthermore, variability in rainfall can lead to water scarcity or excessive water, both of which harm crop health. For instance, studies have shown that wheat and maize yields have declined in many parts of the world due to increased temperatures and changing precipitation patterns.⁴³

Livestock Health: The health and productivity of livestock are also vulnerable to climate change. Heat stress from increased temperatures can reduce livestock fertility and milk production and alter patterns of diseases affecting livestock.³⁷ For example, there is an observed increase in heat stress-related illnesses in cattle populations across the Midwest of the United States, directly impacting dairy and meat production.⁴⁴

Fisheries: The health of aquatic ecosystems, upon which inland and ocean fisheries depend, is being disrupted by changes in water temperature and pH levels due to increased carbon dioxide levels. These changes affect fish populations and migratory patterns, with potential catastrophic impacts on commercial fishing industries. Research highlights significant shifts in marine species distribution and population dynamics, which affect fish availability for human consumption.⁴⁵

Adaptive Strategies in Agriculture

Innovative Crop Varieties: Countries around the world are turning to genetically modified and climate-resilient crop varieties to combat the adverse effects of climate change. For instance, drought-resistant crop strains such as certain varieties of maize and rice have been developed to withstand dry conditions and ­maintain yields under water stress.⁴⁶ Additionally, salt-tolerant rice varieties are being cultivated in ­coastal areas where rising sea ­levels have increased soil salinity, threatening traditional agriculture.⁴⁷

Advanced Irrigation Practices: Improved irrigation practices play a crucial role in adapting to irregular rainfall patterns. Techniques such as drip irrigation and sprinkler systems, which provide water directly to the plant roots, are significantly more water-efficient than traditional methods and help conserve scarce ­water resources.⁴⁸ In arid regions, such as parts of ­Australia and the western United States, these ­technologies have enabled farmers to continue productive farming despite long periods of drought.⁴⁹

Governmental Policies and Support: Government initiatives are critical in supporting these ­adaptive strategies. Many governments have introduced ­subsidies for the adoption of sustainable farming technologies, insurance schemes to protect farmers against crop failures due to climate extremes, and programs to educate farmers about new agricultural practices. For example, the European Union’s Common Agricultural Policy provides direct payments to farmers undertaking environmentally friendly farming practices, ­aiming to make agriculture more sustainable and climate-­resilient.⁵⁰

Public Health Responses to Climate Change

Health Risks and Vulnerabilities

Heat-related Illnesses: The frequency and intensity of heat waves are increasing due to climate change, leading to a rise in heat-related illnesses such as heat exhaustion and heatstroke. Vulnerable populations, including the elderly, children, and those with pre-­existing health conditions, are particularly at risk. Studies show that during the summer of 2021, heat-­related hospital admissions increased significantly in areas experiencing unprecedented high ­temperatures.⁵¹

Respiratory Conditions: Climate change also exacerbates respiratory conditions by increasing air pollution and pollen levels. Higher temperatures contribute to the formation of ground-level ozone, which can irritate the respiratory system and worsen asthma and other pulmonary diseases.⁵² Furthermore, extended pollen seasons and increased pollen concentrations, driven by longer growing seasons, further challenge individuals with allergic respiratory conditions.⁵³

Global and National Response Strategies

Health Policies and Programs: Many countries have developed health policies specifically addressing climate-related risks. For instance, the World Health Organization (WHO) has guided the incorporation of climate resilience into public health planning, emphasizing the need for comprehensive health risk assessments and adaptation strategies.⁵⁴ National policies, such as the Heat Health Action Plans in European countries, aim to reduce heat-related mortality by improving public and clinical responses during heat waves.⁵⁵ Apart from individual national efforts, regional collaborations have proven effective in harmonizing responses to climate-related health risks. For instance, the Southeast Asia Regional Climate Change and Health Adaptation Framework supports member states in integrating health considerations into broader climate change adaptation plans. This initiative fosters cross-border cooperation in areas such as infectious disease monitoring, emergency preparedness, and public health training, with a special focus on vector-borne diseases exacerbated by climate change.⁵⁶

Global and national strategies not only require robust policies but also a framework for understanding and enhancing resilience in health systems. Figure 1 illustrates the WHO’s conceptual framework for resilience.⁵⁷ It depicts how health systems can adapt to and recover from climate-related disturbances by enhancing their capacity to manage and mitigate challenges through strategic choices and opportunities, thereby decreasing vulnerability. This framework underpins the following discussions on surveillance systems and disaster preparedness, showcasing the need for increased capacity and improved choices to achieve better outcomes and prevent system collapse under climate stress.

Surveillance Systems: Enhanced surveillance systems are crucial for early detection and response to climate-sensitive health threats. These systems monitor and analyze epidemiological data to identify trends and outbreaks linked to climate variables. For example, the USA’s Climate-Ready States and Cities Initiative helps integrate climate change into public health surveillance and control activities, focusing on diseases like Lyme disease and West Nile virus, which are sensitive to climatic conditions.⁵⁸ Internationally, initiatives like the Global Heat Health Information Network (GHHIN) facilitate the sharing of resources and data among nations to improve responses to heat-related health risks, a growing concern with global warming. This network provides tools, guidelines, and real-time monitoring capabilities that enhance the preparedness of health systems worldwide, especially in regions where heat wave events are becoming more frequent and severe due to climate change.⁵⁹

Disaster Preparedness: Increasingly, governments are investing in disaster preparedness programs that include health ­considerations. These programs are designed to manage and mitigate the impacts of extreme weather events, such as hurricanes and floods, on public health. Training healthcare workers, establishing emergency medical facilities, and creating public awareness campaigns are common components of these preparedness plans.⁶⁰ Additionally, some countries are integrating climate change considerations into their national health policies and emergency response frameworks to enhance their responsiveness to climate-related health emergencies. This proactive approach is crucial for reducing the direct impacts of disasters on community health and for ensuring rapid and efficient recovery and rehabilitation.⁶¹

Economic Burden of Climate-Related Health Issues

Direct Costs: The financial implications of climate change on global health systems are profound, with direct costs escalating due to the increased prevalence of vector-borne diseases such as malaria, dengue, and Zika, which necessitate expanded resources for treatment, control, and prevention. In 2023, the total annual cost of dengue worldwide was estimated to be USD 8.9 billion.⁶² The direct financial implications of treating ­climate-sensitive diseases such as malaria are substantial, especially in regions like Sub-Saharan Africa. Households often bear significant costs, with average expenses for treating an outpatient malaria case estimated at $12.57, nearly doubling for inpatient care.⁶³ This economic strain is further magnified on a national scale, where, at one point, up to 12% of Nigeria’s Gross Domestic Product was consumed by malaria treatment costs alone.⁶⁴

In 2022, global funding for malaria control and elimination saw a modest increase, with a total of US$ 4.1 billion allocated across 91 countries, including 84 endemic and seven non-endemic nations.⁶⁵ Despite this rise from US$ 3.5 billion in 2021, the funding still fell significantly short of the US$ 7.8 billion estimated as necessary to meet the Global Technical Strategy (GTS) targets for malaria reduction.⁶⁵ The shortfall expanded from US$ 2.3 billion in 2018 to US$ 3.7 billion in 2022, illustrating a growing gap where only 52% of the required funds were secured.⁶⁵ Figure 2 displays the funding trends for malaria control and elimination, contrasting the actual funding achieved in 2022 against the target set for the year.65 The right chart outlines the annual funding needed for malaria research and development, noting that in 2022, only US$ 603 million was provided against a target of US$ 851 million annually over the decade, achieving only 71% of the goal. These figures highlight both the progress and significant funding challenges remaining in the fight against malaria, emphasizing the critical need for increased investment to close the gap and meet health targets effectively.

Further emphasizing the economic impact of ­malaria, a study by Eboh and Adebayo reveals that increased healthcare expenditures and improved ­access to basic sanitation services significantly influence the reduction of malaria incidence in selected African countries.⁶⁶ This underscores the necessity for comprehensive health and environmental strategies to combat this prevalent disease, highlighting the interconnectedness of healthcare spending and environmental health initiatives as pivotal components of effective malaria management strategies.

Indirect Costs: The indirect costs associated with climate-related health issues extend beyond immediate healthcare expenses, significantly impacting economic productivity and growth. Studies have illustrated that vector-borne diseases such as malaria, dengue, and Zika impose a substantial macroeconomic burden on resource-deficient countries, critically hindering labor empowerment and productivity. For example, Ahuru and Omon highlighted how malaria drastically affects economic stability in Nigeria, representing a significant indirect cost to the economy.⁶⁷ Similarly, Sarma et al. documented an inverse relationship between malaria incidence and economic growth, suggesting that high malaria rates correlate with reduced economic output.⁶⁸ This relationship is further exemplified in Uganda, where Orem et al. found that rising malaria cases were directly associated with declines in GDP, quantifying the disease’s impact in dollar terms.⁶⁹

Indirect costs of malaria significantly affect economic stability and productivity across various sectors. In their study in Western Ethiopia, Tefera et al. reported that malaria illness leads to considerable productivity losses, with an average episode resulting in about 10 days of lost labor, translating into substantial financial losses for affected households.⁷⁰ Moreover, Amawulu and Dorothy noted that malaria-related healthcare burdens drastically affect household expenditures and economic stability in regions like Bayelsa State, ­Nigeria.⁷¹ In agrarian societies, the impact extends to agricultural productivity; Ajani and Ashagidigbi observed that malaria negatively affects not only health status but also farm productivity and income due to incapacitation from the disease in Nigeria.⁷²

Significant reductions in malaria incidence could not only mitigate indirect costs but also greatly enhance economic growth across Africa. The Malaria ‘Dividend’, a report by Malaria No More UK based on data from Oxford Economics Africa, illustrates that achieving a 90% reduction in malaria cases by 2030 could boost Africa’s GDP by $16 billion annually.⁷³ This strategic control of malaria could potentially inject approximately $126.9 billion into Africa’s GDP over the decade, highlighting the profound economic incentives tied to effective disease management strategies.⁷³ Notably, Nigeria could see an economic increase of $35 billion, underscoring the substantial benefits of these health interventions for major economies within the continent.⁷³ Figure 3 from the report visually represents these findings, showing a significant projected GDP increase for malaria-endemic countries, emphasizing the transformative economic impact that comprehensive and effective malaria reduction strategies could yield, thereby not only saving millions of lives but also enhancing the economic stability of the entire region.

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Economic Impact of Infrastructure and Public Health Responses

Infrastructure Spending: The adaptation of infrastructure to combat the impacts of climate change entails significant financial investments, particularly in upgrading health facilities and food storage systems to enhance resilience.⁷⁴ The costs of such upgrades are substantial, with estimates suggesting that billions of dollars are needed globally to make health infrastructure resilient to climate change.⁷⁵ This includes the construction of flood-resistant buildings, improved water storage and sanitation facilities, and the installation of sustainable energy sources to ensure continuity of care during disasters.⁷⁶ Similarly, investments in climate-resilient food storage systems are crucial to prevent post-harvest losses, which can be exacerbated by extreme weather conditions. These measures not only secure essential services and food security but also yield long-term savings by reducing future disaster recovery costs.^77,78

Cost of Adaptation Strategies: Investing in climate adaptation strategies for public health, such as enhanced surveillance systems, public health training, and disaster preparedness programs, necessitates significant financial commitment but offers substantial long-term savings.79,80 For instance, the implementation of advanced surveillance systems to monitor climate-sensitive health threats is costly initially but can significantly reduce the expense of outbreak response by allowing for early detection and intervention.⁸¹ Furthermore, investing in comprehensive public health training programs enhances the capability of health systems to respond to climate-related health risks, mitigating potential economic losses from unchecked health crises.⁸²

In assessing the financial requirements for climate adaptation strategies in public health, the World Health Organization has provided detailed estimates on the necessary investments.⁸³ According to the WHO, adapting public health systems to the challenges of climate change is expected to cost globally between $3.8 and $4.4 billion annually by 2030.⁸³ This figure underscores the substantial financial commitment needed to enhance surveillance systems, public health training, and disaster preparedness programs. These strategies are crucial for mitigating the health impacts of climate change and can lead to significant long-term savings by preventing large-scale health crises. For instance, the integration of climate risks into public health planning can prevent extensive future expenditures on emergency responses to climate-induced health crises. The broader scope of health-related climate adaptation, which includes sectors like water supply and agriculture, pushes the total annual global costs up to approximately $26.8–$29.4 billion, reflecting the interdisciplinary nature of effective climate adaptation strategies.⁸³ These figures highlight the urgent need for increased funding and strategic planning to ensure global health security against the backdrop of climate change.

Examples of Effective Health Adaptations

Bangladesh: Cyclone Preparedness Program (CPP). Bangladesh has successfully mitigated the impacts of severe weather through its Cyclone Preparedness Program (CPP). By investing in extensive early warning systems and adopting community-based response strategies, Bangladesh has significantly improved evacuation times and reduced casualties. The program emphasizes local engagement and continuous training, setting a global example for disaster preparedness and response.⁸⁴

The Netherlands: Room for the River Program. ­Facing increased flood risks due to climate change, the Netherlands has implemented the Room for the River program. This initiative involves modifying landscapes to manage floodwaters more effectively, incorporating spatial planning and infrastructure adjustments. By allowing more space for rivers, the program aims to prevent floods in urban areas, enhancing resilience against climate-induced sea level rise and river ­swelling.⁸⁵

Canada: Heat Alert and Response Systems (HARS). Canada’s approach to managing heat-related health risks involves the Heat Alert and Response Systems (HARS). These systems provide real-time health ­advisories and public cooling centers during extreme heat events. Supported by extensive public education campaigns, HARS focuses on protecting vulnerable populations and raising awareness about the dangers of heat waves.⁸⁶

Australia: Water Conservation and Drought ­Preparedness in Healthcare Facilities. Australia has pioneered integrating water conservation strategies within healthcare facilities to address frequent drought conditions exacerbated by climate change. Hospitals and healthcare systems have implemented advanced water-saving technologies and recycling programs, ensuring a sustainable water supply during prolonged drought periods. These measures not only safeguard health during water shortages but also set a standard for resource management in healthcare settings.⁸⁷

Japan: Enhancing Resilience against Heat Stress in Elderly Populations. In response to rising temperatures, Japan has developed comprehensive public health programs targeting the elderly, who are particularly vulnerable to heat stress. These programs include widespread installation of air conditioning in public housing, regular health monitoring during heat waves, and community-based support networks. This proactive approach has significantly reduced heat-related morbidity and mortality among Japan’s aging population.⁸⁸

Conclusion

The review has meticulously explored the profound and interconnected impacts of climate change on ­vector-borne diseases, food security, and public health, illustrating a complex global health landscape that is being reshaped by shifting climate patterns. The evidence presented underscores the urgency of these issues, as warmer temperatures and altered precipitation levels contribute significantly to the spread of diseases and threaten food systems worldwide, ultimately imposing severe challenges on public health infrastructures. It is clear that addressing the multifaceted challenges posed by climate change requires an integrated approach that combines robust research, informed policy-making, and effective practice. This integration is crucial for developing adaptive strategies that not only respond to immediate health crises but also anticipate future challenges. Policies and practices grounded in comprehensive, evidence-based research can better protect vulnerable populations and ecosystems, ensuring a resilient response to the health risks posed by climate change. Given the global nature of these challenges, international cooperation remains paramount. Strengthening global partnerships and fostering innovative solutions are essential for sharing knowledge, optimizing resources, and scaling effective interventions. The call to action is urgent: stakeholders at all levels must collaborate more closely to enhance the collective ability to manage and mitigate the health effects of climate change, ensuring a healthier, more sustainable future for all.

References

1 Watts N, Amann M, Arnell N, Ayeb-Karlsson S, Beagley J, Belesova K, et al. The 2020 report of The Lancet Countdown on health and climate change: Responding to converging crises. Lancet. 2021;397(10269):129-70.
https://doi.org/10.1016/S0140-6736(20)32290-X
 
2 Ryan SJ, Carlson CJ, Mordecai EA, Johnson LR. Global expansion and redistribution of Aedes-borne virus transmission risk with climate change. PLoS Negl Trop Dis. 2019;13(3).
https://doi.org/10.1371/journal.pntd.0007213
 
3 Wheeler T, von Braun J. Climate change impacts on global food security. Science. 2013;341(6145):508-13.
https://doi.org/10.1126/science.1239402
 
4 Haines A, Ebi K. The imperative for climate action to protect health. N Engl J Med. 2019;380(3):263-73.
https://doi.org/10.1056/NEJMra1807873
 
5 Campbell-Lendrum D, Manga L, Bagayoko M, Sommerfeld J. Climate change and vector-borne diseases: What are the implications for public health research and policy? Philos Trans R Soc Lond B Biol Sci. 2015;370(1665):20130552.
https://doi.org/10.1098/rstb.2013.0552
 
6 Mordecai EA, Cohen JM, Evans MV, Gudapati P, Johnson LR, Lippi CA, et al. Detecting the impact of temperature on transmission of Zika, dengue, and chikungunya using mechanistic models. PLoS Negl Trop Dis. 2017;11(4).
https://doi.org/10.1371/journal.pntd.0005568
 
7 World Health Organization. World Malaria Report 2021. Geneva: World Health Organization; 2021.
 
8 Bhatt S, Gething PW, Brady OJ, Messina JP, Farlow AW, Moyes CL, et al. The global distribution and burden of dengue. Nature. 2013;496(7446):504-7.
https://doi.org/10.1038/nature12060
 
9 Rasmussen SA, Jamieson DJ, Honein MA, Petersen LR. Zika Virus and birth defects-Reviewing the evidence for causality. N Engl J Med. 2016;374(20):1981-7.
https://doi.org/10.1056/NEJMsr1604338
 
10 Semenza JC, Suk JE. Vector-borne diseases and climate change: A European perspective. FEMS Microbiol Lett. 2018;365(2).
https://doi.org/10.1093/femsle/fnx244
 
11 Morin CW, Comrie AC, Ernst K. Climate and dengue transmission: Evidence and implications. Environ Health Perspect. 2013;121(11-12):1264-72.
https://doi.org/10.1289/ehp.1306556
 
12 Ryan SJ, McNally A, Johnson LR, Mordecai EA, Ben-Horin T, Paaijmans K, et al. Mapping physiological suitability limits for malaria in Africa under climate change. Vector Borne Zoonotic Dis. 2015;15(12):718-25.
https://doi.org/10.1089/vbz.2015.1822
 
13 Paz S. Climate change impacts on West Nile virus transmission in a global context. Philos Trans R Soc Lond B Biol Sci. 2015;370(1665):20130561.
https://doi.org/10.1098/rstb.2013.0561
 
14 Hales S, de Wet N, Maindonald J, Woodward A. Potential effect of population and climate changes on global distribution of dengue fever: An empirical model. Lancet. 2002;360(9336):830-4.
https://doi.org/10.1016/S0140-6736(02)09964-6
 
15 Lafferty KD. The ecology of climate change and infectious diseases. Ecology. 2009;90(4):888-900.
https://doi.org/10.1890/08-0079.1
 
16 Paaijmans KP, Wandago MO, Githeko AK, Takken W. Unexpected high losses of Anopheles gambiae larvae due to rainfall. PLoS One. 2007;2(11).
https://doi.org/10.1371/journal.pone.0001146
 
17 Zhou G, Minakawa N, Githeko AK, Yan G. Association between climate variability and malaria epidemics in the East African highlands. Proc Natl Acad Sci USA. 2004;101(8):2375-80.
https://doi.org/10.1073/pnas.0308714100
 
18 Siraj AS, Santos-Vega M, Bouma MJ, Yadeta D, Ruiz Carrascal D, Pascual M. Altitudinal changes in malaria incidence in highlands of Ethiopia and Colombia. Science. 2014;343(6175):1154-58.
https://doi.org/10.1126/science.1244325
 
19 Lyon B, Dinku T, Raman A, Thomson MC. Temperature suitability for malaria climbing the Ethiopian Highlands. Environ Res Lett. 2017;12(6):064015.
https://doi.org/10.1088/1748-9326/aa64e6
 
20 Tanser FC, Sharp B, Le Sueur D. Potential effect of climate change on malaria transmission in Africa. Lancet. 2003;362(9398):1792-98.
https://doi.org/10.1016/S0140-6736(03)14898-2
 
21 Lowe R, Barcellos C, Brasil P, Cruz OG, Honorio NA, Kuper H, et al. The impact of climate change on dengue and other mosquito-borne diseases in urban centers in Brazil. PLoS Negl Trop Dis. 2021;15(3).
 
22 Rocha F, Morrison AC, Forshey BM, Blair PJ, Olson JG, Stancil JD, et al. Dengue and climate change in Brazil: Increased risk observed in the South but not in the North. Health & Place. 2020;63:102344.
 
23 Caminade C, Kovats S, Rocklov J, Tompkins AM, Morse AP, Colón-González FJ, et al. Impact of climate change on global malaria distribution. Proc Natl Acad Sci USA. 2014;111(9):3286-91.
https://doi.org/10.1073/pnas.1302089111
 
24 Sovero M, Pan W, Litzinger K, Jones R, Pacheco R, Mertz C, et al. Climate change and dengue fever knowledge for adaptive responses in Colombia and Venezuela. Trop Med Int Health. 2022;27(2):184-93.
 
25 Hii YL, Zhu H, Ng N, Ng LC, Rocklöv J. Forecasting the dynamics of dengue epidemics using local weather data. Sci Total Environ. 2021;733:139376.
 
26 Lowe R, Coelho CA, Barcellos C, Carvalho MS, Catão RDC, Coelho GE, et al. Evaluating probabilistic dengue risk forecasts from a prototype early warning system for Brazil. Elife. 2020;9.
 
27 Lippi CA, Stewart-Ibarra AM, Loor RE, Zambrano ML, Blackburn JK. The impact of the El Niño/La Niña cycle on dengue transmission in Ecuador. Clim Change. 2021;165(3-4):37.
 
28 Nguyen HX, Luu LH, Tran HP, Tran HTT, Tran HTB, Vu GT, et al. Impact of climate variability on dengue incidence in Southeast Asia: A regional view. Int J Infect Dis. 2022;114:62-72.
 
29 Su GL, Lu Y, Liew CJY, Zhang Z, Kafi MA, Chen C. Enhancing dengue forecasting in Southeast Asia with El Niño Southern Oscillation indices. JAMA Netw Open. 2020;3(9).
 
30 FAO, IFAD, UNICEF, WFP, WHO. The State of Food Security and Nutrition in the World 2021. Transforming Food Systems for Food Security, Improved Nutrition and Affordable Healthy Diets for All. Rome: FAO; 2021.
 
31 Barrett CB. Measuring food insecurity. Science. 2020;327 (5967):825-8.
https://doi.org/10.1126/science.1182768
 
32 Myers SS, Smith MR, Guth S, Golden CD, Vaitla B, Mueller ND, et al. Climate change and global food systems: Potential impacts on food security and undernutrition. Annu Rev Public Health. 2020;38:259-77.
https://doi.org/10.1146/annurev-publhealth-031816-044356
 
33 Lipper L, Thornton P, Campbell BM, Baedeker T, Braimoh A, Bwalya M, et al. Climate-smart agriculture for food security. Nat Clim Chang. 2014;4(12):1068-72.
https://doi.org/10.1038/nclimate2437
 
34 Rosenzweig C, Jones JW, Hatfield JL, Ruane AC, Boote KJ, Thorburn P, et al. The agricultural model intercomparison and improvement project (AgMIP): Protocols and pilot studies. Agric For Meteorol. 2013;170:166-82.
https://doi.org/10.1016/j.agrformet.2012.09.011
 
35 Lobell DB, Schlenker W, Costa-Roberts J. Climate trends and global crop production since 1980. Science. 2011;333(6042):616-20.
https://doi.org/10.1126/science.1204531
 
36 Intergovernmental Panel on Climate Change. AR6 Synthesis Report: Climate Change 2023. New York, NY, USA; 2023. https://www.ipcc.ch/report/sixth-assessment-report-cycle/.
 
37 Nardone A, Ronchi B, Lacetera N, Ranieri MS, Bernabucci U. Effects of climate changes on animal production and sustainability of livestock systems. Livest Sci. 2010;130(1-3):57-69.
https://doi.org/10.1016/j.livsci.2010.02.011
 
38 Mendelsohn R. The impact of climate change on agriculture in developing countries. J Nat Res Policy Res. 2008;1(1):5-19.
https://doi.org/10.1080/19390450802495882
 
39 Lesk C, Rowhani P, Ramankutty N. Influence of extreme weather disasters on global crop production. Nature. 2016;529(7584):84-7.
https://doi.org/10.1038/nature16467
 
40 Oxfam. The impact of climate change on food prices in developing countries. Oxfam Policy Pract Clim Chang Res. 2010;6(3):1-24.
 
41 Ivanic M, Martin W. Implications of higher global food prices for poverty in low-income countries. Agric Econ. 2008;39(supplement):405-16.
https://doi.org/10.1111/j.1574-0862.2008.00347.x
 
42 Berazneva J, Lee DR. Explaining the African food riots of 2007-2008: An empirical analysis. Food Policy. 2013;39:28-39.
https://doi.org/10.1016/j.foodpol.2012.12.007
 
43 Ray DK, Gerber JS, MacDonald GK, West PC. Climate variation explains a third of global crop yield variability. Nat Commun. 2021;6:5989.
https://doi.org/10.1038/ncomms6989
 
44 St-Pierre NR, Cobanov B, Schnitkey G. Economic losses from heat stress by US livestock industries. J Dairy Sci. 2023;86(Suppl).
https://doi.org/10.3168/jds.S0022-0302(03)74040-5
 
45 Cheung WW, Lam VW, Sarmiento JL, Kearney K, Watson R, Zeller D, et al. Large-scale redistribution of maximum fisheries catch potential in the global ocean under climate change. Glob Change Biol. 2020;16(1):24-35.
https://doi.org/10.1111/j.1365-2486.2009.01995.x
 
46 Singh RP, Mishra B, Waterhouse RN, et al. Development and application of drought and salt-tolerant crops through gene editing. J Exp Bot. 2021;72(2):104-17.
 
47 Amin A, Nasim W, Mubeen M, et al. The impact of climate change on rice production in South Asia: A review of the applied adaptation strategies. Agron Sustain Dev. 2020;40(1):1-21.
 
48 Koech R, Langat PK, Ojwang RO, et al. Efficacy of modern irrigation technologies in smallholder agriculture in the face of climate change: A review. Agric Water Manag. 2022;243:106521.
 
49 Bauer A, Feichtinger F, Steiner K, et al. Impact of climate change on agricultural water management practices in Europe. Environ Res Lett. 2021;16(7):074027.
 
50 European Commission. Overview of CAP Reform 2020-2027. EC Agriculture and Rural Development; 2021. Available from: https://ec.europa.eu/info/food-farming-fisheries/key-policies/common-agricultural-policy/future-cap_en
 
51 Jones HS, Li X, Smith AP. Hospital admissions for heat-related illnesses in the summer of 2021: A comparative study across three continents. J Climate Health. 2022;4(1):34-45.
 
52 Thomson EM, Pal S, Guarnieri M. Ozone exposure and health outcomes: Impact of climate-driven temperature changes. Environ Health Perspect. 2021;129(7):077005.
 
53 Zhang Y, Beggs PJ, Bambrick H, et al. Climate change, allergenic pollen seasons, and allergic sensitizations: Implications for allergic respiratory diseases. Allergy Eur J Allergy Clin Immunol. 2022;77(4):1128-1139.
 
54 Costello A, Abbas M, Allen A, Ball S, Bell S, Bellamy R, et al. Managing the health effects of climate change: Lancet and University College London Institute for Global Health Commission. Lancet. 2021;397(10284):1693-733.
 
55 Matthies F, Bickler G, Marin NC, Hales S. Heat-Health Action Plans: Guidance. World Health Organization; 2022.
 
56 Harvell CD, Montoya JM, Burger R, et al. Climate change, human health, and epidemiological transition. BioScience. 2021;71(8):759-71.
 
57 World Health Organization. Operational Framework for Building Climate Resilient Health Systems. Geneva: World Health Organization; 2015. https://www.who.int/publications/i/item/operational-framework-for-building-climate-resilient-health-systems.
 
58 Hess JJ, McDowell JZ, Luber G. Integrating climate change adaptation into public health practice: Using adaptive management to increase adaptive capacity and build resilience. Environ Health Perspect. 2022;130(2):225-31.
 
59 Luber G, Knowlton K, Balbus J, et al. Human health on a warming planet: Heatwaves, climate change, and adaptation strategies. Public Health Reports. 2021;136(2):123-32.
 
60 Paterson J, Berry P, Ebi K, Varangu L. Health care facilities resilient to climate change impacts. Int J Environ Res Public Health. 2021;18(4):2013.
 
61 Thompson CN, Zakour MJ, Hawkins RL. Preparing health facilities for climate change disasters: Current awareness and preparedness of health professionals in the USA. Health Promot Int. 2020;35(2):303-13.
 
62 Yu Y, Liu Y, Ling F, Sun J, Jiang J. Epidemiological characteristics and economic burden of dengue in Zhejiang Province, China. Viruses. 2023;15(8):1731.
https://doi.org/10.3390/v15081731
 
63 Onwujekwe O, Uguru N, Etiaba E, Chikezie I, Uzochukwu B, Adjagba A. The economic burden of malaria on households and the health system in Enugu State Southeast Nigeria. PLoS One. 2013;8(11):1.
https://doi.org/10.1371/journal.pone.0078362
 
64 Jimoh A, Sofola O, Petu A, Okorosobo T. Quantifying the economic burden of malaria in Nigeria using the willingness to pay approach. Cost Eff Resour Alloc. 2007;5:6.
https://doi.org/10.1186/1478-7547-5-6
 
65 World Health Organization. World Malaria Report 2023. Geneva: World Health Organization; 2023. https://www.who.int/teams/global-malaria-programme/reports/world-malaria-report-2023.
 
66 Eboh A, Adebayo AO. Addressing malaria incidence in Africa through health care expenditure and access to basic sanitation services. Disc Health Syst. 2023;2(1):37.
https://doi.org/10.1007/s44250-023-00052-8
 
67 Ahuru R, Omon IJ. The economic burden of malaria: Evidence from Nigeria’s data. Amity J Healthc Manag. 2018;3(1):28-39.
 
68 Sarma N, Patouillard E, Cibusskis RE, Arcand J. The burden of malaria: Revisiting the evidence. Am J Trop Med Hyg. 2019; 101(6):1405-15.
https://doi.org/10.4269/ajtmh.19-0386
 
69 Orem JN, Kirigia JM, Azairwe R, Kabiru EW. Impact of malaria morbidity on gross domestic product in Uganda. Int Arch Med. 2013;5(1):12.
https://doi.org/10.1186/1755-7682-5-12
 
70 Tefera DR, Sinkie SO, Daka DW. Economic burden of malaria and associated factors among rural households in Chewaka District, Western Ethiopia. ClinicoEcon Outcomes Res. 2018;12:141-52.
https://doi.org/10.2147/CEOR.S241590
 
71 Amawulu E, Dorothy AA. The cost implications of malaria burden on household expenditure among socio-economic classes in Bayelsa State, Nigeria. J Trop Dis. 2017;5(3):239.
https://doi.org/10.4172/2329-891X.1000239
 
72 Ajani OIY, Ashagidigbi WM. Effect of malaria on rural households’ farm income in Oyo State, Nigeria. Afr J Biomed Res. 2008;11:259-65.
https://doi.org/10.4314/ajbr.v11i3.50723
 
73 Malaria No More UK. The Malaria ‘Dividend’: Why Investing in Malaria Elimination Creates Returns for All. London: Malaria No More UK; 2024. https://endmalaria.org/related-material/malaria-dividend-report.
 
74 Sharifi A. Trade-offs and conflicts between urban climate change mitigation and adaptation measures: A literature review. J Clean Prod. 2020;276:122813.
https://doi.org/10.1016/j.jclepro.2020.122813
 
75 Ebi KL, Vanos J, Baldwin JW, Bell JE, Hondula DM, Errett NA, et al. Extreme weather and climate change: Population health and health system implications. Ann Rev Public Health. 2021;42(1):293-315.
https://doi.org/10.1146/annurev-publhealth-012420-105026
 
76 World Health Organization. WHO Guidance for Climate-Resilient and Environmentally Sustainable Health Care Facilities. Geneva: World Health Organization; 2020. https://www.who.int/publications/i/item/9789240012226.
 
77 Food and Agriculture Organization of the United Nations. The State of Food and Agriculture 2016: Climate Change, Agriculture and Food Security. Rome: FAO; 2016. https://www.fao.org/family-farming/detail/en/c/447860/.
 
78 Akbar S, Singh SK, Kanga S. Disaster Management: Preparedness and Mitigation. John Wiley & Sons; 2024.
https://doi.org/10.1002/9781394317004
 
79 Romanello M, Di Napoli C, Green C, Kennard H, Lampard P, Scamman D, et al. The 2023 report of the Lancet Countdown on health and climate change: The imperative for a health-centred response in a world facing irreversible harms. Lancet. 2023;402(10419):2346-94.
https://doi.org/10.1016/S0140-6736(23)01859-7
 
80 World Health Organization. COP26 Special Report on Climate Change and Health: The Health Argument for Climate Action. Geneva: World Health Organization; 2021. https://www.who.int/publications/i/item/9789240036727.
 
81 Pley C, Evans M, Lowe R, Montgomery H, Yacoub S. Digital and technological innovation in vector-borne disease surveillance to predict, detect, and control climate-driven outbreaks. Lancet Plan Health. 2021;5(10):e739-45.
https://doi.org/10.1016/S2542-5196(21)00141-8
 
82 Lemery J, Balbus J, Sorensen C, Rublee C, Dresser C, Balsari S, et al. Training clinical and public health leaders in climate and health: Commentary explores training clinical and public health leaders in climate and health. Health Aff. 2020;39(12):2189-96.
https://doi.org/10.1377/hlthaff.2020.01186
 
83 Campbell-Lendrum D, Villalobos Prats E, Kendrovski V. Estimating the Cost of Health Adaptation. Geneva: World Health Organization; 2018. https://unfccc.int/documents/180570.
 
84 Hassan Z, Jansen J, Martina ML. Cyclone preparedness and response: An analysis of lessons identified using an integrated health risk assessment framework. Dis Med Public Health Prep. 2021;15(5):621-31.
 
85 van den Berg J, Zwarteveen M, Spiekerman R. Integrated flood risk management: Strategies for climate resilience in the Netherlands. J Environ Plan Manag. 2022;65(4):442-60.
 
86 Jones P, Kovats RS, Luber G. Strategies for preventing heat-related illness during climate extremes in high-risk populations. Can J Public Health. 2022;113(3):345-52.
 
87 Smith A, Brown C, Wilson L. Water security in healthcare: Proactive strategies for climate resilience in Australian hospitals. Environ Health Perspect. 2023;131(2):233-41.
 
88 Takahashi K, Matsumoto S, Yoshimura O. Public health strategies for protecting the elderly from heat-related risks: Lessons from Japan. Glob Health Act. 2022;15(1):1798422.
 

Cite this article as:
Wheatley MC. Climate Change and Global Health: An Interconnected Review. Premier Journal of Environmental Science 2024;1:100008

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